Tristem SA

STEM CELL THERAPY

Key Aspects of Stem Cell Decline

Functional Exhaustion:

Stem cells lose their ability to self-renew and differentiate, failing to repair damaged tissue efficiently, particularly in muscle, blood, and the immune system.

Reduced Numbers:

While some populations maintain numbers, most stem cell pools experience a decrease in total number, with significant decline often noted after age 70-75.

Metabolic Stress:

Decline in pathways like AMPK and SIRT1 leaves stem cells vulnerable to energy depletion.

Environmental Factors:

The environment surrounding stem cells changes, reducing signaling required for proper function. Increased inflammation ("inflammaging") disrupts stem cell function.

Molecular & Cellular Damage:

  • DNA Damage:Accumulation of damage triggers senescence or apoptosis
  • Epigenetic Dysregulation:Changes in DNA methylation alter gene expression
  • Telomere Shortening:Limits the lifespan of rapidly dividing stem cells

STEM CELL THERAPY

Choosing the right Stem Cell Supplements

Choosing a stem cell supplement can be tough. With so many options making different claims, the best approach is to look closely at what sets each product apart. Try to ignore the marketing hype and focus on quality and proven effectiveness, as flashy advertising does not guarantee a superior product.